Joseph R. Winer, PhD

Scientist, California Pacific Medical Center Research Institute


E-Mail:  [email protected]
Address: Box 0560
550 16th Street, 2nd Floor
San Francisco, CA 94159

Dr. Winer's research combines wearable devices and disease biomarkers to explore how tracking sleep and other factors in everyday life can provide information about brain health, cognitive trajectories, and neurodegenerative processes. He conducted his postdoctoral training at Stanford University where he focused on PET imaging and fluid biomarkers of Alzheimer's disease and Lewy body disease.

Research Interests

  • Sleep neurobiology
  • Neurodegenerative disease
  • Dementia and cognitive decline
  • Biomarkers of disease
  • Wearable devices

Selected Publications

Visit PubMed to see additional publications
 
  1. Winer, J., Vossler, H., Young, C., Romero, A., Smith, V., Shahid, M., Abdelnour, C., Wilson, E., Anders, D., Pacheco Morales, A., Andreasson, K., Yutsis, M., Henderson, V., Davidzon, G., Mormino, E., Poston, K. (2025). 18F-PI-2620 tau PET is associated with cognitive and motor impairment in Lewy body disease. Brain Communications, 7(1), fcae458.

  2. Winer, J., Lok, R., Weed, L., He, Z., Poston, K., Mormino, E., Zeitzer, J. (2024). Impaired 24-h activity patterns are associated with an increased risk of Alzheimer’s disease, Parkinson’s disease, and cognitive decline. Alzheimer’s Research & Therapy, 16(1), 35.
  3. Winer, J., Lok, R., Ekelmans, A., Bueno, F., Poston, K., Zeitzer, J., During, E. (2023). Isolated REM sleep behavior disorder is associated with altered 24-hour rest-activity measures. Frontiers in Sleep, 2.

  4. Winer, J., Deters, K., Kennedy, G., Jin, M., Goldstein-Piekarski, A., Poston, K, Mormino, E. (2021). Short and long sleep duration associations with amyloid burden and cognition in aging. JAMA Neurology, 78(10), 1187–1196.

  5. Winer, J., Morehouse, A., Fenton, L., Ayangma, L., Reed, M., Kumar, S., Harrison, T., Baker, S., Jagust, W., Walker, M. (2021). Tau and β-amyloid burden predict actigraphy-measured and self-reported impairment and misperception of human sleep. Journal of Neuroscience, 41(36) 7687-7696.

  6. Winer, J., Mander, B., Kumar, S., Reed, M., Baker, S., Jagust, W., Walker, M. (2020). Sleep disturbance forecasts β-amyloid accumulation across subsequent years. Current Biology, 30, 4291-4298.

  7. Winer, J., Mander, B., Helfrich, R., Maass, A., Harrison, T., Baker, S., Knight, R., Jagust, W., Walker, M. (2019). Sleep as a potential biomarker of tau and β-amyloid burden in the human brain. Journal of Neuroscience, 39(32), 6315-6324.

  8. Winer J., Maass A., Pressman P., Stiver J., Schonhaut D., Baker S., Kramer J., Rabinovici G., Jagust W. (2018). Associations between tau, β-amyloid, and cognition in Parkinson disease. JAMA Neurology, 75(2), 227-235.