Katie L. Stone, PhD

Senior Scientist, California Pacific Medical Center Research Institute

E-Mail: [email protected] or [email protected]

Box 0560
550 16th Street, 2nd Floor
San Francisco, CA 94158

Additional Websites:

California Pacific Medical Center, Research Institute

Dr. Stone is Senior Scientist at CPMC and Adjunct Professor of Epidemiology and Biostatistics at the University of California, San Francisco. She is an epidemiologist with over 25 years of experience conducting large-scale multi-center cohort studies exploring the interrelationships between sleep and health outcomes, including falls and fractures, cognitive impairment and dementia, cardiovascular disease and mortality. Dr. Stone directed the MrOS (Osteoporotic Fractures in Men) and SOF Sleep Studies, in which sleep was measured objectively and subjectively in over 6,000 older adults. Findings from these studies have been reported in nearly 200 peer-reviewed publications. Dr. Stone also leads multi-center randomized trials to test whether treating sleep problems such as insomnia improves health and wellbeing in adults of all ages. She is principal Investigator for the PCORI-funded trial, Comparative Effectiveness of Zolpidem and Cognitive Behavioral Therapy for Insomnia in Rural Adults (COZI).

Research Interests

  • Insomnia and sleep disorders in older adults

Selected Publications

A full list of publications can be accessed at MyNCBI

  1. Posner AB, Tranah GJ, Blackwell T, Yaffe K, Ancoli-Israel S, Redline S, Leng Y, Zeitzer JM, Chen DM, Webber KR, Stone KL. Predicting incident dementia and mild cognitive impairment in older women with nonparametric analysis of circadian activity rhythms in the Study of Osteoporotic Fractures. Sleep. 2021 May 8:zsab119. Epub ahead of print. PMID: 33964167.
  2. Xiao Q, Qian J, Evans DS, Redline S, Lane NE, Ancoli-Israel S, Scheer FAJL, Stone K; Osteoporotic Fractures in Men (MrOS) Study Group. Cross-Sectional and Prospective Associations of Rest-Activity Rhythms with Circulating Inflammatory Markers in Older Men. J Gerontol A Biol Sci Med Sci. 2021 Apr 5:glab095. Epub ahead of print. PMID: 33822930.
  3. Leary EB, Watson KT, Ancoli-Israel S, Redline S, Yaffe K, Ravelo LA, Peppard PE, Zou J, Goodman SN, Mignot E, Stone KL. Association of Rapid Eye Movement Sleep With Mortality in Middle-aged and Older Adults. JAMA Neurol. 2020; 77(10):1241-1251. PMC7550971.
  4. Landrigan CP, Rahman SA, Sullivan JP, Vittinghoff E, Barger LK, Sanderson AL, Wright KP Jr, O'Brien CS, Qadri S, St Hilaire MA, Halbower AC, Segar JL, McGuire JK, Vitiello MV, de la Iglesia HO, Poynter SE, Yu PL, Zee PC, Lockley SW, Stone KL, Czeisler CA; ROSTERS Study Group. Effect on Patient Safety of a Resident Physician Schedule without 24-Hour Shifts. N Engl J Med. 2020; 382(26):2514-2523. PMC7405505.
  5. Ensrud KE, Kats AM, Schousboe JT, Langsetmo L, Vo TN, Blackwell TL, Buysse DJ, Ancoli-Israel S, Stone KL; Study of Osteoporotic Fractures. Multidimensional sleep health and subsequent health-care costs and utilization in older women. Sleep. 2020; 43(2): zsz230. PMC7017952.
  6. Blackwell T, Kriesel DR, Vittinghoff E, O'Brien CS, Sullivan JP, Viyaran NC, Rahman SA, Lockley SW, Barger LK, Halbower AC, Poynter SE, Wright KP Jr, Yu PL, Zee PC, Landrigan CP, Czeisler CA, Stone KL; ROSTERS Study Group. Design and recruitment of the randomized order safety trial evaluating resident-physician schedules (ROSTERS) study. Contemp Clin Trials. 2019; 80:22-33. PMC6482052.
  7. Stone KL, Lui LY, Christen WG, Troen AM, Bauer DC, Kado D, Schambach C, Cummings SR, Manson JE. Effect of Combination Folic Acid, Vitamin B(6) , and Vitamin B(12) Supplementation on Fracture Risk in Women: A Randomized, Controlled Trial. J Bone Miner Res. 2017;32(12):2331-2338. PMC5734110.
  8. Wallace ML, Stone K, Smagula SF, Hall MH, Simsek B, Kado DM, Redline S, Vo TN, Buysse DJ; Osteoporotic Fractures in Men (MrOS) Study Research Group. Which Sleep Health Characteristics Predict All-Cause Mortality in Older Men? An Application of Flexible Multivariable Approaches. Sleep 2018; 41(1). PMC5806578.
  9. Zeitzer JM, Blackwell T, Hoffman AR, Cummings S, Ancoli-Israel S, Stone K; Osteoporotic Fractures in Men (MrOS) Study Research Group. Daily Patterns of Accelerometer Activity Predict Changes in Sleep, Cognition, and Mortality in Older Men. J Gerontol A Biol Sci Med Sci. 2018; 73(5): 682-7. PMC5905637. 
  10. Stone KL, Blackwell TL, Ancoli-Israel S, Barrett-Connor E, Bauer DC, Cauley JA, Ensrud KE, Hoffman AR, Mehra R, Stefanick ML, Varosy PD, Yaffe K, Redline S. Sleep disordered breathing and risk of stroke in older community dwelling men. SLEEP 2016; 39(3):531-40. PMC4763364.
  11. Yaffe K, Laffan AM, Harrison SL, Redline S, Spira AP, Ensrud KE, Ancoli-Israel S, Stone KL. Sleep-disordered breathing, hypoxia, and risk of mild cognitive impairment and dementia in older women. JAMA. 2011; 306(6):613-9.