Dr. Lane is a nationally recognized expert in the medical management of osteoporosis and osteoarthritis. She is an associate editor for Seminars in Rheumatic Diseases, Rheumatology, and Arthritis Research and Therapy; an editorial board member for Journal of Bone and Mineral Research, Journal of Rheumatology and consultant editor for Annals of Internal Medicine, and Journal of Bone and Joint Surgery. Dr. Lane is affiliated with the Department of Epidemiology and Biostatistics, Division of Clinical Trials and Multicenter Studies, University of California, San Francisco, and is a collaborating researcher with the San Francisco Coordinating Center. Dr. Lane is a fully funded NIH researcher on osteoporosis, bone health, and osteoarthritis. Dr. Lane welcomes junior faculty and graduate students who investigate the epidemiology and treatment of musculoskeletal diseases to the work in her group.

Research Interests

• Osteoarthritis
• Osteoporosis

Selected Publications

1. 1.  Lane NE, Lin P, Christiansen L, et al. Association of mild acetabular dysplasia with an increased risk of    incident hip osteoarthritis in elderly white women: the study of osteoporotic fractures. Arthritis Rheum. 2000 Feb; 43(2):400-4. PMID: 10693881

   2.Baker-Lepain JC, Lynch JA, Parimi N, McCulloch CE, Nevitt MC, Corr M, Lane NE. Variant alleles of the Wnt antagonist FRZB are determinants of hip shape and modify the relationship between hip shape and osteoarthritis. Arthritis Rheum. 2012 May; 64(5):1457-65. PMID: 22544526. PMCID: PMC3340442

   3.Evans DS, Cailotto F, Parimi N, Valdes AM, Castaño-Betancourt MC, Liu Y, Kaplan RC, Bidlingmaier M, Vasan RS, Teumer A, Tranah GJ, Nevitt MC, Cummings SR, Orwoll ES, Barrett-Connor E, Renner JB, Jordan JM, Doherty M, Doherty SA, Uitterlinden AG, van Meurs JB, Spector TD, Lories RJ, Lane NE. Genome-wide association and functional studies identify a role for IGFBP3 in hip osteoarthritis. Rheum Dis. 2014 Jun 13. PMID: 24928840. PMCID: PMC4449305

   4.Bauer DC, Hunter DJ, Abramson SB, Attur M, Corr M, Felson D, Heinegård D, Jordan JM, Kepler TB,Lane  NE, Saxne T, Tyree B, Kraus VB; Osteoarthritis Biomarkers Network. Classification of osteoarthritis     biomarkers: a proposed approach. Osteoarthritis Cartilage. 2006 Aug;14(8):723-7. doi: 10.1016/j.joca.2006.04.001. Epub 2006 Jun 2. PMID: 16733093.

   5. Sanchez-Lopez E, Coras R, Torres A, Lane NE, Guma M. Synovial inflammation in osteoarthritis progression. Nat Rev Rheumatol. 2022 May;18(5):258-275. doi: 10.1038/s41584-022-00749-9. Epub 2022 Feb 14. PMID: 35165404; PMCID: PMC9050956.

   6. Wei J, Hunter D, Lane NE, Wu J, Zeng C, Lei G, Zhang Y. Weight Loss Induced by Antiobesity Medications and All-Cause Mortality Among Patients With Knee or Hip Osteoarthritis. Arthritis Rheumatol. 2024 Apr;76(4):577-586. doi: 10.1002/art.42754. Epub 2023 Dec 6. PMID: 38053480.

   7. Wei J, Hunter D, Lane NE, Wu J, Zeng C, Lei G, Zhang Y. Weight Loss Induced by Antiobesity Medications and All-Cause Mortality Among Patients With Knee or Hip Osteoarthritis. Arthritis Rheumatol. 2024 Apr;76(4):577-586. doi: 10.1002/art.42754. Epub 2023 Dec 6. PMID: 38053480.

   8. Zeng C, Lane NE, Li X, Wei J, Lyu H, Shao M, Lei G, Zhang Y. Association between bariatric surgery with long-term analgesic prescription and all-cause mortality among patients with osteoarthritis: a general population-based cohort study. Osteoarthritis Cartilage. 2021 Oct;29(10):1412-1417. doi: 10.1016/j.joca.2021.05.063. Epub 2021 Jul 19. PMID: 34293442.

   Visit PubMed to see additional publications